{"id":24742,"date":"2014-05-21T00:08:30","date_gmt":"2014-05-21T00:08:30","guid":{"rendered":"https:\/\/www.institutodeengenharia.org.br\/?p=24742"},"modified":"2014-05-21T15:05:51","modified_gmt":"2014-05-21T15:05:51","slug":"livro-toxicologia-in-silico-fundamentos-e-aplicacoes","status":"publish","type":"post","link":"https:\/\/www.institutodeengenharia.org.br\/site\/2014\/05\/21\/livro-toxicologia-in-silico-fundamentos-e-aplicacoes\/","title":{"rendered":"Livro – Toxicologia in silico: fundamentos e aplica\u00e7\u00f5es"},"content":{"rendered":"

Toxicologia In Silico: Fundamentos e aplica\u00e7\u00f5es \u00e9 o primeiro livro em l\u00edngua portuguesa sobre o assunto, publicado pelo prof. Carlos E. Matos. <\/p>\n

A Toxicologia In Silico representa um avan\u00e7o da Toxicologia Preditiva e consiste na aplica\u00e7\u00e3o de tecnologias computacionais para identifica\u00e7\u00e3o do potencial de toxicidade, a partir das caracter\u00edsticas f\u00edsico-qu\u00edmicas e estruturais das subst\u00e2ncias qu\u00edmicas, visando a racionaliza\u00e7\u00e3o da experimenta\u00e7\u00e3o animal, a custo-efetividade em triagens, a melhoria a compreens\u00e3o dos mecanismos de a\u00e7\u00e3o t\u00f3xica e a constru\u00e7\u00e3o de evid\u00eancias de toxicidade junto aos modelos biol\u00f3gicos tradicionais e alternativos. <\/p>\n

Diversos modelos in silico s\u00e3o \u00fateis para avalia\u00e7\u00e3o de novas mol\u00e9culas, princ\u00edpios ativos, contaminantes ambientais, produtos de biotransforma\u00e7\u00e3o, produtos de degrada\u00e7\u00e3o e impurezas em diversos contextos. <\/p>\n

A aplica\u00e7\u00e3o de modelos in silico tem sido realizada e proposta em diversos pa\u00edses e diferentes contextos. No Canad\u00e1, foram utilizados modelos in silico para a avalia\u00e7\u00e3o e categoriza\u00e7\u00e3o do invent\u00e1rio local testes no programa nacional de seguran\u00e7a qu\u00edmica. <\/p>\n

CLIQUE AQUI<\/a> PARA MAIS INFORMA\u00c7\u00d5ES. <\/p>\n

Autor: InterTox <\/b><\/p>\n","protected":false},"excerpt":{"rendered":"

Autor – Carlos E. Matos dos Santos, Editora Pl\u00eaiade. Exemplar dispon\u00edvel na biblioteca do Instituto de Engenharia <\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[27,6],"tags":[],"class_list":{"0":"post-24742","1":"post","2":"type-post","3":"status-publish","4":"format-standard","6":"category-instituto-de-engenharia","7":"category-noticias"},"yoast_head":"\nLivro - Toxicologia in silico: fundamentos e aplica\u00e7\u00f5es - Instituto de Engenharia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.institutodeengenharia.org.br\/site\/2014\/05\/21\/livro-toxicologia-in-silico-fundamentos-e-aplicacoes\/\" \/>\n<meta property=\"og:locale\" content=\"pt_BR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Livro - Toxicologia in silico: fundamentos e aplica\u00e7\u00f5es - Instituto de Engenharia\" \/>\n<meta property=\"og:description\" content=\"Autor - Carlos E. 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